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Welcome
to the website of the INTERPRET project (IST-1999-10310)
funded by the European Comission.
Project
duration: January 1st, 2000 - December 31st, 2002
We
aim to facilitate the use of magnetic resonance spectroscopy (MRS) for
improved diagnosis and therapy of patients with brain tumours and other
space occupying lesions. Spectra, easily acquired alongside commonplace
MR imaging (MRI) procedures, uniquely delineate biochemistry of human
tissue in situ. Although MRS gives significantly improved brain tumour
categorisation, it is not widely used, partly because radiologists have
difficulty in interpreting spectral data. We therefore aim
to develop a user-friendly computer program for spectral
classification. Systems
development will be informed by (a) a large "training set" of data
contributed
by members of the consortium and (b) new spectra acquired under agreed
protocols.
Automated pattern recognition techniques will be developed for tumour
classification
together with an intuitive interface. The program will promote wider
use
of MRS, hence reducing the need for distressing and dangerous brain
biopsies.
The
INTERPRET project is finished now, those are its main achievements:
- several
user-friendly prototype decision support systems (DSS) for clinical
use, for single voxel (SV) and multivoxel (MV) 1H studies of brain
tumours. Those are our SCIENTIFIC DSS prototypes.
- a
database with web access for use by all INTERPRET members containing
validated clinical, MRS and MRI data from human brain tumours and
normal controls.
- automated
data manipulation and format conversion software.
- consensus
clinical, MRS and MRI data acquisition protocols.
Now we
extend our research on non-invasive brain tumour diagnosis in the frame
of eTumour and HealthAgents
Click here to read
the INTERPRET
final summary report
Web page maintenance after INTERPRET project completion (Dec 31st 2002)
funded by Generalitat de Catalunya
(grants CIRIT SGR2005-194, SGR2005-863, XT 2002-48, XT2004-51) and MCYT (grant
SAF2002-10280-E) |